
Autocamtide-2-related inhibitory peptide
CAS No. 167114-91-2
Autocamtide-2-related inhibitory peptide( —— )
Catalog No. M23750 CAS No. 167114-91-2
Autocamtide-2-related inhibitory peptide is a highly specific and potent inhibitor of CaMKII with an IC50 of 40 nM.
Purity : >98% (HPLC)






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Biological Information
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Product NameAutocamtide-2-related inhibitory peptide
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NoteResearch use only, not for human use.
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Brief DescriptionAutocamtide-2-related inhibitory peptide is a highly specific and potent inhibitor of CaMKII with an IC50 of 40 nM.
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DescriptionAutocamtide-2-related inhibitory peptide is a highly specific and potent inhibitor of CaMKII with an IC50 of 40 nM.
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In VitroIt is found that Autocamtide-2-related inhibitory peptide (a novel synthetic peptide ATP) is a potent inhibitor of CaM-kinase II with an IC50 of 40 nM, which is active in the presence or absence of Ca2+/calmodulin. It is 50 and 500 times more potent than CaMK-(281-302Ala286) and KN-93,respectively, under the assay condition used.
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In Vivo——
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Synonyms——
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PathwayEndocrinology/Hormones
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TargetCaMK
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RecptorCaMKII
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Research Area——
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Indication——
Chemical Information
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CAS Number167114-91-2
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Formula Weight1822.1
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Molecular FormulaC80H143F3N22O22
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Purity>98% (HPLC)
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SolubilityDMSO:10 mM
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SMILESO=C(N[C@@H](CCC(N)=O)C(N[C@@H](CCC(O)=O)C(N[C@@H](C)C(N[C@@H](C(C)C)C(N[C@@H](CC(O)=O)C(N[C@@H](C)C(N[C@H](C(O)=O)CC(C)C)=O)=O)=O)=O)=O)=O)[C@H](CCCNC(N)=N)NC([C@H](CCCNC(N)=N)NC([C@H](CC(C)C)NC([C@H](C)NC([C@H](CCCCN)NC([C@@H](N)CCCCN)=O)=O)=O)=O)=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Ishida A, Kameshita I, Okuno S, Kitani T, Fujisawa H. A novel highly specific and potent inhibitor of calmodulin-dependent protein kinase II. Biochem Biophys Res Commun. 1995;212(3):806-812. doi:10.1006/bbrc.1995.2040
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